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脉络宁注射液对糖尿病下肢动脉硬化闭塞症患者的疗效观察

Effect of Mailuoning injection on lower extremity diabetic atherosclerotic obliterans
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摘要 目的观察脉络宁注射液治疗糖尿病下肢动脉硬化闭塞症的临床疗效。方法采用随机数字表法将入选的2型糖尿病下肢动脉硬化闭塞症患者分为治疗组120例和对照组60例,治疗组静脉滴注脉络宁注射液及速效胰岛素,1次/d;对照组静脉滴注前列地尔,1次/d,治疗4刷后观察临床疗效。结果治疗组总有效率为95.0%、对照组为83.3%,两组总有效率比较,差异有统计学意义(t=3.724,P〈0.01)。结论脉络宁注射液可减少或消除血栓彤成,用于糖尿病下肢动脉硬化闭塞症的治疗安全有效。 Objective To observe the effect and safety of Mailuoning Injection(MLN) in treating patients with type 2 diabetes mellitus accompanying lower extremity atherosclerotic obliterans. Methods The selected patients were assigned by randomized digital table to a treated group (120 cases treated with MLN) and a control group (60 cases treated with alprostadil). The clinical efficacy was assessed after 4 weeks of treatment. Results The total effective rate in the treated group was 95.0%, better than that in the control group, 83.3% (P〈 0.01 ). Conclusion MLN has the effect of activating blood circulation,dissolving stasis and dredging collaterals reducing the formation of thrombi. MLN is effective and safe when applied in clinical practice for the treatment of lower extremity diabetic atherosclerotic obliterans.
出处 《国际中医中药杂志》 2011年第8期684-685,共2页 International Journal of Traditional Chinese Medicine
关键词 脉络宁注射液 2型糖尿病 下肢动脉硬化闭塞症 Mailuoning injection Type 2 diabetes mellitus Lower extremity atherosclerotic obliterans
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