摘要
目的观察心衰患者血清B型钠利尿肽(BNP)、高敏C反应蛋白(hsCRP)的水平变化,研究BNP、hsCRP与心功能状况之间的关系。方法本研究选择心力衰竭患者50例,正常对照45例,观察其BNP和hsCRP的变化。结果心衰患者的BNP和hsCRP较对照组明显升高,随着心功能状态的恶化,BNP和hsCRP逐渐升高,且心力衰竭越重,BNP和hsCRP水平越高,两组对比差异具有统计学意义(P<0.05,P<0.01)。结论血清BNP和hsCRP测定可以作为临床上判断心力衰竭程度的一个参考指标,对评估心衰患者的病情和临床疗效一定的价值。
Objective To observe the changes of blood - serum high sensitivity C - reactive protein, BNP level, and study the association between high sensitivity C - reactive protein, blood - serum BNP level and congestive heart failure patients. Methods The blood - serum BNP and high sensitivi- ty C -reactive protein concentration in 50 patients with congestive heart failure and 45 controls were determined and contrasted. Results The blood -serum BNP and high sensitivity C -reactive protein levels in congestive heart failure patients was significantly higher than that of the controls (P 〈 0.05, P 〈 0.01 ). And with the increase of degree of congestive heart failure, the blood - serum BNP and high sensitivity C -reactive protein levels gradually increased. Conclusions The assay of the blood - serum BNP and high sensitivity C -reactive protein concentration is one reference index in judgement of the degree of congestive heart failure,and play an important role in the classification of cardiac function and clinical curative effect.
出处
《医药论坛杂志》
2011年第11期42-44,共3页
Journal of Medical Forum
关键词
B型钠利尿肽
高敏C反应蛋白
心衰
Brain natriuretic peptide
High sensitivity C -reactive protein
Congestive heart failure