缺血性脑梗死住院患者的糖脂代谢异常研究

The study of abnormal glucose and lipid metabolism on the in- patients with ischemic stroke

目的探讨中国常州缺血性脑梗死患者糖脂代谢异常的流行状况。方法选取本院神经内科及内分泌科2007年4月-2008年4月住院的缺血性脑梗死患者，共收集771例，未确诊糖尿病的对象均进行口服葡萄糖耐量试验（OGTT）以判断糖代谢状况。结果缺血性脑梗死住院患者中确诊糖尿病患者达41．8％，糖代谢受损23．4％，总的糖代谢异常患病率为65．2％。若不进行OGTT，单纯依靠空腹血糖进行诊断，将有58．5％的糖尿病患者被漏诊。结论脑梗死住院患者中大多数合并糖脂代谢异常，需要通过OGTT及时准确地发现这些合并糖代谢异常的患者，以减少脑梗死再发。

Objective To study the epidemiology of abnormal glucose and lipid metabolism on the in - patients with ischemic stroke in China. Methods Total 771 cases of in - patients with ischemie stroke who hospitalized in department of neurology and endocrinology of our hospital from 04 - 2007 to 04 - 2008 were enrolled in this study. To identify the condition of glucose metabolism,all diagnosis undetermined patients received oral glucose tolerance test.Results Among inpatients with iscbemie stroke,41.8% patients were finally diagnosed diabetes,and 23.4% were impaired glucose tolerance.The prevalence of abnormal glucose metabolism in total was 65.2% .If diabetes in the in- patients with iscbemic stroke was diagnosed only by fasted plasma glucose instead of oral glucose tolerance test,58.5% diabetic patients would be missed diagnosis.Conclusion The majority of in - patients with iscbemie stroke exists abnormal glucose and lipid metabolism.h is necessary to promptly and exactly diagnose these patients with abnormal glucose metabolism by oral glucose tolerance test,and then decreases recurrence of stroke.