加替沙星与左氧氟沙星治疗泌尿系统感染的临床疗效及经济学分析

Effectivenss and Pharmacoeconmic Analysis of Gatifloxacin and Levofloxacin in the Treatment of Urinary Sytem Infection

目的比较加替沙星与左氧氟沙星治疗泌尿系统感染的临床疗效及成本-效果分析。方法采用随机5组静脉治疗及药物经济学原理对两种治疗方案进行成本-效果分析。结果加替沙星组与左氧沙星组治疗泌尿系统感染的有效率分别为92.86%、88.46%（P〉0.05）;不良反应发生率分别为7.1%、9.0%（P〉0.05）;成本-效果比（C/E）分别为7.99、6.53。与左氧氟沙星组相比,加替沙星组每增加一个单位效果需多花费37.43元。结论左氧氟沙星治疗泌尿系统感染的成本-效果比优于加替沙星。

Objective To compare the cost-effectiveness ratio of gatifloxacin and levofloxacin in the treatment of patints with infection in urinary system.Methods Principle of pharmaconomics wsa adopted to analyze the cost-effectiveness of two trestment schemes.Results The effective rates of gatifloxacin group and ievoflosacin group in the treatment of urinary system intection were 92.86% and 88.46%（P0.05） respectively;the incidence rates of adverse reacrions were 7.1% and 9.0%（P0.05）;The cost-effectiveness rauos（C/E） were 7.99 and 6.53 respectively.The cost for every one unit increment of effectiveness tor gatifloxacin group was 37.43 Yuan more than that of the levofloxacin group.Conclusion The cost-effectiveness ratio of levotloxccin is superior to that of gatifloxacin in treatment of urinary system infection.