雷米芬太尼无痛分娩在临床的应用

Clinical Application of remifentanil for painless labor

目的观察雷米芬太尼行无痛分娩的临床有效性和安全性。方法 40例足月头位初产妇随机分为雷米芬太尼镇痛组(Ⅰ组)和未行镇痛对照组(Ⅱ组),每组20例。观察分娩过程中产妇的VAS评分、Ramsay镇静评分及胎心率FHR、及胎儿娩出后1、5 min时Apgar评分。结果两组产妇的生命体征都比较平稳。镇痛组产妇在宫口开到4～6 cm时的镇静评分升高,VAS评分明显降低。两组的FHR和新生儿出生后1、5 min Apgar评分均在正常范围。结论雷米芬太尼可安全用于无痛分娩,镇痛有效,无明显不良反应。

Objective To observe the clinical efficacy and safety of remifentanil for painless labor. Methods 40 first term primiparas were randomly assigned into remifentanil analgesic group （ Group Ⅰ ） and non - analgesic group （ Group Ⅱ ） with 20 cases each. Evaluate and record the VAS and the Ramsay sedation scores of each primiparas during the labor process, and the fatal heart rate （FHR） and the 1 and 5 minutes Apgar scores of neonates. Results The vital signs of the primigravidas in both groups are steady. In Group Ⅰ, the sedation score raises and VAS reduces significantly when the dilatation of cervix is up to 4 -6 cm. The FHR and the 1 and 5 minutes Apgar scores of neonates are within the normal limits in both groups. Conclusion Remifentanil for painless labor is effective without significant side effect.