7例特殊类型的癫痫发作后神经功能缺损患者的临床特征分析

A clinical study of seven patients with special syndrome of post-epileptic dysfunction

目的：探讨癫痫患者临床发作后神经功能缺损（PEND）的特点。方法：回顾分析7例特殊形式的PEND病例的特点，并进行相关的文献回顾分析。结果：7例PEND患者中，6例出现于癫痫持续状态（SE）后，5例存在颅内结构性病灶。PEND存在多种形式，如肢体瘫痪（Todd麻痹）、失语、认知障碍、凝视麻痹及偏盲等。神经功能缺损时间可持续达3个月。结论：PEND多发生于SE之后，患者多存在颅内器质性脑损害的基础，PEND存在多种形式，持续时间从效天到3个月，多数预后良好。

Objective：To investigate clinical features of post-epileptic nerves dysfunction （PEND）. Methods： Seven patients with special syndromes of PEND were retrospectively analyzed and related literature was re viewed. Results：Six patients with PEND manifested status epileptieus and 5 patients had brain structural lesion out of the 7 patients. PEND had different syndromes,including post-epileptic paralysis, post-epileptic aphasia, cognitive disorder,gaze palsy, hemianopsia and so on. The duration of dysfunction could last for 3 months. Conclusions： The great majority of patients with PEND manifest a status epilepticus and have brain structural le sions. PEND includes various syndromes and can last from several days to 3 months with a rather good prognosis in most eases.