270例单纯胆囊经腹腔镜切除术患者围手术期抗菌药物应用分析

Application of antibiotics among 270 cases of patients with laparoscopic cholecystectomy during perioperative period

目的了解医院腹腔镜胆囊切除术患者围手术期抗菌药物应用情况。方法随机抽取2009-2010年医院肝胆外科腹腔镜胆囊切除术手术患者270例,依据《抗菌药物临床应用指导原则》,调查围手术期抗菌药物的预防性应用情况。结果调查的270例腹腔镜胆囊切除术患者在围手术期全部预防性应用了抗菌药物,使用率100.0%;药物种类主要以硝咪唑类、头孢菌素类、青霉素类等为主,抗菌药物使用率排前5位的药物分别是奥硝唑氯化钠注射液、注射用阿莫西林钠氟氯西林钠、注射用头孢甲肟、硫酸异帕米星注射液、甲硝唑注射液注,其使用率分别为26.30%、16.44%、12.80%、8.82%、8.13%。结论应加强围手术期抗感染药物使用的管理和监督,促进临床医师合理用药。

OBJECTIVE To understand the operation of laparoscopic cholecystectomy hospital perioperative application of antimicrobial agents.METHODS From 2009 to 2010 270 atients with hepatobiliary surgery by laparoscopic cholecystectomy were investigated,according to ＂Guiding Principles of clinical use of antibiotics＂,the survey of perioperative prophylactic application of antibiotics.RESULTS We investigated 270 cases of laparoscopic cholecystectomy surgery patients with perioperative prophylactic use of all antimicrobial agents,was 100.0%.The main categories of drugs to nitrate imidazole,cephalosporins,penicillins,mainly,the use rates were respectively 26.30%,16.44%,12.80%,8.82% and 8.13%,respectively.CONCLUSION It should strengthen the perioperative use of anti-infective management and supervision,and promote rational drug clinicians.