指标监控限制性使用抗菌药物临床效果分析

Clinical effect of restrictive use of antibiotics by indicators monitoring

目的控制抗菌药物使用档次,用药时限,降低抗菌药物使用率和医院感染率。方法对2008年1月-2009年12月住院患者采用前瞻监测方法,制定抗菌药物使用指标分解到科室,限制头孢三代及以上抗菌药物的临床应用。结果指标监控限制性使用抗菌药物实施两年来,抗菌药物使用率由2008年的64.54%降至61.33%,合理用药使用率、围手术期用药率、细菌检验率大幅提高。结论指标监控限制性使用抗菌药物可有效降低抗菌药物使用率,同时提高抗菌药物合理用药率和细菌检验率,减少耐药菌株和医院感染的发生。

OBJECTIVE To control the antimicrobial levels,and use of time,to reduce antimicrobial usage and hospital infection.METHODS The hospitalized patients from Jan 2008 to Dec 2009 were analyzed by using prospective monitoring method.The antimicrobial use index into sections was formulated,the clinical application of antimicrobial agents of three generations of cefazolin or above was limited.RESULTS Monitor restrictive use antimicrobial index of implementation of two years,the use rate of antimicrobial agents decreased from 64.54% in 2008 to 61.33%.Rational drug use utilization rates,perioperative use rate,bacteria inspection rate has increased significantly.CONCLUSION Restrictive use of antibiotics by indicators monitoring can effectively reduce the use rate of antibiotics,simultaneously,improve the rational use rate of antibiotics and bacterial examination rate and reduce the drug resistant strains and nosocomial infection.