卫氏并殖吸虫童虫的生物学特性

BIOLOGICAL CHARACTERISTICS OF THE JUVENILE PARAGONIMUS WESTERMANI

目的： 了解卫氏并殖吸虫童虫的生物学特性。方法： 从锯齿华溪蟹分离卫氏并殖吸虫囊蚴， 以每鼠８０～１５０ 个囊蚴感染小鼠和大鼠， 分别于感染后１０～３０ ｄ 和８０～５８０ ｄ 分期解剖小鼠和大鼠， 检查虫体。观察童虫的寿命、在死亡宿主或５～８ ℃生理盐水中， 存活的时间及对新宿主的侵袭力。结果： 童虫的寿命较长， 大鼠于感染囊蚴５８０ ｄ 死亡后检出的童虫仍可转种其它大鼠； 同样， 小鼠体内的童虫也可转种其它小鼠， 童虫寿命不受某一个体宿主寿命限制。在转续宿主间转换， 可延长童虫的寿命， 并保持其活力和侵袭力。死亡小鼠体内的童虫及低温保存的童虫， 仍有较强的活力与侵袭力。结论： 童虫具有较强的活力与侵袭力，

AIM: To observe the biological characteristics of the juvenile of Paragonimus westermani. METHODS: Kunmin strain mice and Wistar rats inoculated orally with 100-150 metacercariae of Paragonimus westermani were autopsied 10-30 days and 80-580 days after infection, respectively. Life\|span, survival time in dead hosts or physiological saline at 5℃ to 8 ℃ and invasiveness of juveniles to new hosts were detected by host transfer. RESULTS: All the worms recovered from the mice and rats were stunted juveniles. The worm detection rates in the mice and rats were 19\^3% and 22\^2%-37\^5%, respectively. The life\|span of the juveniles was rather long, being not limited by the life\|span of a host. Host transfer could prolong longevity and preserve invasiveness. The juveniles recovered from dead mice still possess strong vitality and invasiveness. CONCLUSION: The juvenile of P.westermani is an infective stage, having strong vitality and invasiveness.\;