期刊文献+

脑血栓形成溶栓治疗46例临床分析 被引量:2

下载PDF
导出
摘要 目的:探讨脑血栓形成溶栓治疗的有效性,为临床治疗提供参考。方法:脑血栓形成46例患者都采用基于爱通立(rt-PA)的静脉溶栓治疗,分析比较溶栓前后的NIHSS、ESS评分。结果:溶栓前的NIHSS评分为(9.75±3.15)分,溶栓24 h的NIHSS评分为(8.54±2.55)分,14 d的NIHSS评分为(5.32±1.92)分,将不同时间段的NIHSS评分两两配对t检验,结果显示差异均有统计学意义(P<0.05)。溶栓前的ESS评分为(56.12±10.22)分,24 h的ESS评分为(61.15±15.95)分,14 d的ESS评分为(76.75±13.33)分,将不同时间段的ESS评分两两配对t检验,结果显示差异均有统计学意义(P<0.05)。结论:基于rt-PA的静脉溶栓治疗脑血栓形成疗效好,且随着时间的变化逐渐恢复正常,值得临床推广。
出处 《吉林医学》 CAS 2011年第21期4441-4441,共1页 Jilin Medical Journal
  • 相关文献

参考文献6

  • 1Rubiera M,Alvarez-Sabln J,Ribo M,et al.Predictors of Early Arterial Re0cclusion After Tissue Plasminogen Activator-Induced Recanalization in Acute Ischemic Stroke[J].Stroke,2005,36(7): 1452.
  • 2Furlan AJ,Eyding D,Albers GW, et al.Dose Escalation of Desmoteplase for Acute Ischemic Stroke(DEDAS):evidence of safety and efficacy 3 to 9 hours after stroke onset[J].Stroke,2006,37(5): 1227.
  • 3Steiner T,JtRtler E,Ringleb P.Acute stroke therapy:Current developments[J].Nervenarzt,2007,78(10): 1147.
  • 4欧少君,尚孝堂,江蓓湖,王东毅,汪蔚青,杨伟,施佳,刘宗军,金惠根,沈卫峰.急性心肌梗死后存活心肌对急性期严重心律失常的影响[J].上海医学,2003,26(1):45-47. 被引量:5
  • 5许骥,华琦,刘力松,万云高,李东宝,胥照平,姜燕,杨旭,李天德,胡大一,刘荣坤,杨峥.重组人尿激酶原与尿激酶对急性心肌梗死患者纤溶系统影响的比较[J].首都医科大学学报,2005,26(2):132-135. 被引量:35
  • 6中华医学会心血管病学分会,中华心血管病杂志编辑委员会.心血管病治疗指南和建议[M].第4版.北京:人民军医出版杜,2011:47.

二级参考文献14

  • 1Verde P, Fudo T, Kambara H, et al. Coronary thrombolysis with human single-chain urokinase-type plasminogen activator(pro-urokinase) in patients with acute myocardial infarction. Ann Inter Med, 1986,104:345~346.
  • 2Weaver W D, Hartmann J R, Anderson J L, et al. New recombinant glycosylated prourokinase for treatment of patients with acute myocardial infarction. J Am Coll Cardiol, 1994,24:1242~1248.
  • 3Pannel R, Henry T D, Haugland J M, et al. Pro-UK:a study of its stability in plasma and of a mechanism for its selective fibrolytic effect. Blood, 1986,67:1215.
  • 4Frits W, Meyer J, Vermeer F, et al. Comparison of saruplase and alteplase in acute myocardial infarction. Am J Cardiol, 1997,79:727~732.
  • 5Tebbe U, Michels R, Adgey J, et al. Randomized, double-blind study comparing saruplase with streptokinase therapy in acute myocardial infarction: The comapass equivalence trial. J Am Coll Cardol, 1998,31:487~493.
  • 6Braunwald E, Kloner RA. The stunned myocardium: prolonged, postischemic ventricular dysfunction. Circulation, 1982,66:1146-1149.
  • 7Marban E. Myocardial stunning and hibernation. The physiology behind the colloquialisms. Circulation, 1991, 83:681-688.
  • 8Kloner RA, Przyklenk K, Patel B. Altered myocardial states. the stunned and hibernating myocardium. Am J Med, 1989,86(Suppl-lA): 14-22.
  • 9Zimmermann R, Mall G, Rauch B, et al. Residual 201TI activity in irreversible defects as a marker of myocardial viability. Clinicopathological study. Circulation, 1995,91:1016-1021.
  • 10Galli M, Marcassa C, Imparato A, et al. Effects of nitroglycerin by technetium-99m sestamibi tomoscintigraphy on resting regional myocardial hypoperfusion in stable patients with healed myocardial infarction. Am J Cardiol, 1994 ,74:843-848.

共引文献34

同被引文献28

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部