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细胞角蛋白免疫组化染色在胃癌淋巴结转移检测中的价值 被引量:2

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摘要 目的 比较胃癌淋巴结单张切片细胞角蛋白免疫组化(CKIHC) 染色与连续6 张切片HE染色检查结果。方法 选择根治性胃癌切除标本,每枚淋巴结分别行单张切片CKIHC染色和连续6 张切片HE染色。结果 CKIHC染色转移度10 .8%(176/1630 枚) ,转移率72.7% (24/33 例);HE染色转移度6.4% (104/1630 枚) ,转移率66.7% (22/33 例)。两组转移度相比差异有显著性( P< 0.01),但转移率无显著性差异( P> 0.05) 。结论 用CKIHC染色后能发现更多数目的淋巴结转移,其优点是在低倍镜下即可发现淋巴结转移,可大大减轻病理学检查的工作量而又提高淋巴结检查质量。
出处 《实用肿瘤杂志》 CAS 北大核心 1999年第6期365-366,372,共3页 Journal of Practical Oncology
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参考文献4

  • 1张应天.胃癌根治术中淋巴结清除的研究.第十二届全国外科学术会议论文汇编[M].,1993.31-33.
  • 2彭开勤 邵永胜 等.细胞角蛋白免疫组化染色在乳腺癌腋淋巴结转移检测中的价值.第六届中南六省(区)普外学术会议论文汇编[M].,1996.5-8.
  • 3彭开勤,第六届中南六省( 区)普外学术会议论文汇编,1996年,5页
  • 4张应天,第12届全国外科学术会议论文汇编,1993年,31页

同被引文献14

  • 1Lee E, Chae Y, Kim I, et al. Prognostic relevance of immunohistochemically detected lymph node micrometastasis in patients with gastric carcinoma [ J ]. Cancer, 2002, 94 (11) :2867 -2873.
  • 2Morgagni P, Saragoni L, Scarpi E, et al. Lymph node micrometastases in early gastric cancer and their impact on prognosis[J]. World J Surg, 2003,27(5) :558 -561.
  • 3Choi H J, Kim YK, Kim YH, et al. Occurrence and prognostic implications of micrometastases in lymph nodes from patients with submucosal gastric carcinoma [ J ]. Ann Surg Oncol, 2002, 9(1) :13 - 19.
  • 4Fukagawa T, Sasako M, Mann GB, et al. Immunohistochemically detected micrometastases of the lymph nodes in patients with gastric carcinoma [ J ] . Cancer, 2001 , 92 ( 4 ) : 753 - 760.
  • 5Mori M, Mimoro K, Ueo H, et al. Clinical significance of molecular detection of carcinoma cells in lymph nodes and peripheral blood by reverse transcription-polymerase chain reaction in patients with gastrointestinal or breast carcinomas[J].J Clin Oncol , 1998, 16(1): 128-132.
  • 6Lee E, Chae Y, Kim I, et al. Prognostic relevance of immunohistochemically detected lymph node micrometastasis in patients with gastric carcinoma[J]. Cancer, 2002,94(11):2867-2873.
  • 7Morgagni P, Saragoni L, Scarpi E,et al.Lymph node micrometastases in early gastric cancer and their impact on prognosis[J]. World J Surg,2003,27(5):558-561.
  • 8Choi HJ, Kim YK, Kim YH,et al. Occurrence and prognostic implications of micrometastases in lymph nodes from patients with submucosal gastric carcinoma[J]. Ann Surg Oncol, 2002,9(1):13-19.
  • 9Fukagawa T, Sasako M, Mann GB,et al. Immunohistochemically detected micrometastases of the lymph nodes in patients with gastric carcinoma[J]. Cancer, 2001, 92(4):753-760.
  • 10邱文才,王维刚,王志刚,陈刚,席时富,郑起.胃癌腹腔微转移检测及其临床意义[J].中国普通外科杂志,2007,16(9):872-874. 被引量:9

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