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髓系来源的抑制性细胞免疫学特点及其在自身免疫性疾病中的作用 被引量：3

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摘要 髓系来源的抑制性细胞（myeloid—derived suppressorcells，MDSCs）来源于骨髓祖细胞和未成熟的髓系细胞，具有较强的免疫调节功能。MDSCs最初在肿瘤疾病模型中报道，主要与肿瘤细胞的免疫逃逸有关，但是近几年的研究表明MDSCs广泛参与炎症免疫应答，如感染、外伤应激、自身免疫性疾病等。
作者 李海文 戴夫 彭琼 李颖 吴虓
机构地区 安徽医科大学第三附属医院消化内科 解放军第
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2011年第7期667-670,共4页 Chinese Journal of Microbiology and Immunology
关键词 自身免疫性疾病 髓系细胞 抑制性 免疫学特点 免疫调节功能 肿瘤细胞 骨髓祖细胞 疾病模型
分类号 R593 [医药卫生—内科学]
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参考文献26

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二级参考文献36

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共引文献23

同被引文献32

  • 1林其德,邱丽华.原因不明复发性流产与母-胎界面免疫耐受[J].中华妇产科杂志,2006,41(3):145-147. 被引量：26
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  • 6Movahedi K, Guilliams M, Van den Bossche J, et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood, 2008, 111 : 4233-4244.
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  • 10Zhang W, Liang S, Wu J, et al. Human inhibitory receptor immunoglobulin-like transcript 2 amplifies CD11 b + Gr1+ myeloid- derived suppressor cells that promote long-term survival of allografts. Transplantation, 2008. 86 : 1125-1134.

引证文献3

二级引证文献4

中华微生物学和免疫学杂志
2011年 第7期

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