近视眼和LASIK后眼压与角膜厚度的关系

Correlation of intraocular pressure and central corneal thickness in myopic eyes before and after LASIK

目的 :分析原位角膜磨镶术 ( laser in situ keratomileusis,L ASIK)治疗近视眼术前、术后眼压与角膜中央厚度的关系。方法 :2 12只眼采用 L ASIK治疗近视眼。用非接触式眼压计测量术前、术后的眼压以及角膜中央厚度 ,对眼压与术前、术后角膜中央厚度进行相关分析和回归分析。结果 :L ASIK术前眼压与角膜中央厚度呈正相关 ,相关系数 r=0 .2 68,p=0 .0 0 0。术后眼压的改变与切除的角膜厚度的改变也呈正相关 ,与实际切除角膜厚度的相关系数为 r=0 .182 ,p=0 .0 0 8。结论 :角膜中央厚度是影响 NCT眼压测量值的重要因素 ,对于眼压的精确测定一定要考虑角膜中央厚度的影响 。

Object:To analyze the relationship of intraocular pressure( IOP) and central corneal thickness( CCT) in myopic eyes before and after laser in situ keratomileusis( L ASIK) .Methods:The intraocular pressure measured by noncontacttonometerand CCT by ultrasonic pachymetry in2 12 eyes pre- and1month post- L ASIK.Correlation analysis and linear regression analysis were per- formed.Results:There was significantcorrelation between IOP and CCT pre- L ASIK( r=0 .2 68;p=0 .0 0 0 ) .Correlation was also found between the drop of IOP and the ablation depth of CCT post L ASIK( r=0 .182 ;p=0 .0 0 8) .Conclusions:Central corneal thick- ness is an important factor in measuring IOP by NCT and should be considered in precise measurement,particularly in eyes with previous photorefractive surgery.