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软骨细胞培养中细胞去分化和再分化研究进展 被引量：1

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摘要 软骨细胞是软骨组织工程种子细胞的一个重要来源,应用自体软骨细胞构建的组织工程软骨可以成功修复大型哺乳动物关节承重面的缺损.自体软骨细胞移植术作为一种有效和成熟的技术已开始应用于临床关节软骨缺损修复,但软骨组织中的软骨细胞数量较少,接种支架前需要进行足量的扩增才能满足修复缺损的要求.
作者 刘瑾春 刘霞 曹谊林
机构地区 中国医学科学院北京协和医学院整形外科医院研究中心
出处 《中华整形外科杂志》 CAS CSCD 北大核心 2011年第4期318-320,共3页 Chinese Journal of Plastic Surgery
基金 国家自然科学基金青年科学基金项目（30801192）,北京市自然基金（7102134） 高等学校博士学科点专项科研基金（新教师基金课题,200800231078）
关键词 软骨细胞培养 软骨组织工程种子细胞 关节软骨缺损修复 再分化 去分化 组织工程软骨 自体软骨 细胞移植术
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献33

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二级参考文献10

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中华整形外科杂志
2011年 第4期

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