细胞间黏附分子-1基因多态性与类风湿关节炎的关系
摘要
类风湿关节炎（rheumatoidarthritis，RA）是滑膜组织中以滑膜细胞增生和炎症细胞的聚集为特征的慢性自身免疫性疾病，易感基因的研究有助于弄清RA的发病机制，并将可能成为RA的诊断、治疗和判断预后的一个有效指标。免疫球蛋白超家族中的细胞间黏附分子-1（ICAM-1）在炎症细胞的聚集和渗透中起着重要作用。有关研究显示ICAM-1基因多态性与多种免疫性疾病的发生相关，
出处
《中华风湿病学杂志》
CAS
CSCD
北大核心
2011年第8期577-579,共3页
Chinese Journal of Rheumatology
基金
基金项目：浙江省台州市科技计划（100KY05）
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