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维拉佐酮盐酸盐 被引量:2

vilazodone hydrochloride
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摘要 由Trovis Pharma LLC制药公司研制的维拉佐酮盐酸盐(vilazodone hydrochloride)于2011年1月21日由FDA批准上市,商品名为Viibryd,用于治疗成年人重度抑郁症(major depressive disorder,MDD)[1]。Viibryd将以10 mg、20 mg和40 mg片剂上市。
作者 李赛 宫平
机构地区 沈阳药科大学
出处 《中国药物化学杂志》 CAS CSCD 2011年第4期329-329,共1页 Chinese Journal of Medicinal Chemistry
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参考文献4

  • 1US Food and Drug Administration. Drug approval package Vi- ibryd( vilazodone hydrochloride ) tablets [ EB/OL ] : [ 2011 - 01-21 ]. http://www, fda. gov/NewsEvents/Newsroom/ PressAn-Nouncements/ucm240642. htm.
  • 2TIMO H,HENNING B,ROLF G,et al. Synthesis and structure- activity relationship in a class of indolebutylpiperacines as dual- 5-HTIA receptor agonists and sero tonin reuptake inhibitors [ J]. J Med Chem,2004,47(19) :4684 -4692.
  • 3US Food and Drug Administration. Drug approval package Vi- ibryd( vilazodone hydrochloride ) tablets [ EB/OL ]. [ 2011 - 01 -21 ]. http:/www, fda. gov/downloads/Drugs/DrugSafe- ty/UCM 241524.
  • 4pdf. US Food and Drug Administration. Drug approval package Vi- ibryd ( vilazodone hydrochloride) tablets [ EB/OL ]. [ 2011 - 01 -21 ]. http ://www. accessdata, fda. gov/drugsatfda docs/ label/2011/022567 s0001 bl. pdf.

同被引文献20

  • 1HOWLAND R H. Vilazodone: another novel atypical antidepressant drug [ J ]. J Psychosoc Nurs Ment Health Serv,2011,49(3) :19 -22.
  • 2SORBERA L A, RABASSEDA X, SILVESTRE J, et al. Vilazodone hydrochlofide[ J ]. Drugs Fut,2001,26 (3) :247 -252.
  • 3HEINRICH T, BOETTCHER H, GERICKE R, et al. Synthesis and strucatre-activity relationship in a class of indolebutylpiperazines as dual 5-HT1A receptor agonists and serotonin reuptake inhibitors [ J ]. J Med Chem,2004,47(19):4684 -4692.
  • 4A·巴斯.制备5-(4-[4-(5-氰基-3-吲哚基)-丁基]-1一哌嗪基)苯并呋喃-2-甲酰胺的方法:中国,101163698A[P].2008-04-16.
  • 5陈牧.抗抑郁症药物维拉佐酮的制备方法:中国,102180868A[P].2011-03-30.
  • 6SUZUKI Y, TAKAHASHI H. Formylation of phe- nols with electron-withdrawing groups in strong acids. Synthesis of substituted salicylaldehydes [ J ]. Chem Pharm Bu11,1983,31 (5) :1751 - 1753.
  • 7TSUNEO S. Synthesis of 2, 3-dihydrobenzofurans from ethyl 2-acylphenoxyacetates [ J] Bull Chem Soc Jpn, 1985,58 ( 10 ) : 2821 - 2825.
  • 8CHARLES C P, ALBERT P, BERNARD H V. Hy- drolysis and chlorination of three 2-chloroethylamines [ J ]. J Org Chem, 1947,12 (2) : 308 - 321.
  • 9HENRY F R, BRENDA J H, DARRYL B H, et al. 5-Substituted indoles via sodium indoline-2-sulfonate [J]. Org Prep Proced Int,1985,17(6) :391 -399.
  • 10宗利,郭文娟.一种5-(哌嗪-1-基)苯并呋喃-2-羧酸乙酯的合成方法:CN,103965148[P].2014-08-06.

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