河南地区阻塞性睡眠呼吸暂停低通气综合征患者高血压患病率及相关因素研究

Study on the association between obstructive sleep apnean-hypopnea syndrome and prevalence of hypertension and the research on related factor in Henan province

目的了解河南地区阻塞性睡眠呼吸暂停低通气综合征（0sAHs）患者高血压患病情况及相关影响因素，为制定相应干预措施提供依据。方法纳入在河南省睡眠呼吸障碍诊疗中心确诊的OSAHS患者共302例，均经过病史询问、体格检查，并在睡眠监测室进行至少7h的夜间多导睡眠监测，监测患者的血压，血氧饱和度，体质量指数，呼吸暂停低通气指数等，使用SPSS13．0软件包进行统计分析，采用X^2检验研究高血压患病率。结果纳入的OSAHS患者中高血压患病率为62．9％，男性明显高于女性，高血压患病率与呼吸暂停低通气指数的高低呈正相关，夜间最低血氧饱和度〈80％患者的高血压患病率显著高于其他患者。结论OSAHS与高血压患病率关系密切，呼吸暂停低通气指数、夜间最低血氧饱和度、体质量指数等睡眠相关指标与高血压患病率有统计学相关性。

Objective To investigate the prevalence of hypertension among obstructive sleep apnea- hypopnea syndrome （OSAHS） patients and associated factors. Methods A total of 302 patients with OSAHS were enrolled in this study. Medical history interview, blood pressure measurement and an inhospital polysomnogram were performed for all the patients. Some related factor such as the apeanhypopnea index （AHI）, minimum SpO2, body mass index （BMI） were studied. SPSS 13.0 software package was used for data analyzing, and prevalence rates of hypertension were compared by chi-square test. Results The incidence of hypertension in all patients with OSAHS is 62.9%, and the male is more than the female. The prevalence of hypertension increased with AHI increases, and the prevalence of hypertension in patients with the minimum SpO2〈 80% was higher significantly than that in other patients. Conclusions There was a close relationship between OSAHS and the prevalence of hypertension. There were statistical correlation between age,AHI,BMI and hypertension.