未婚女性抗心磷脂抗体检查结果分析

Relationship between anticardiolipin antibodies and induced abortion

目的:探讨未生育女性与人工流产抗心磷脂抗体(ACA)的关系。方法:对进行优生健康检查的已婚未育育龄妇女742例,未妊娠者319例,妊娠者423例,采用酶联免疫吸附法(ELISA法)测定血清ACA。结果:①未育女性ACA阳性率11.46%,其中未妊娠者阳性率12.06%,已妊娠者阳性率11.11%;②有人工流产史者ACA阳性率较无人工流产史者增高(P<0.05),随人工流产次数增多ACA阳性率有增高趋势;③一次人工流产史者中距人工流产时间≤2年者较>2年者阳性率增高(P<0.05)。结论:妊娠不增加ACA阳性的发生率;人工流产是引起ACA阳性的重要原因;ACA随着时间的推移有消退的可能。

Objective：To explore the relationship between anticardiolipin antibodies（ACA） and induced abortion.Methods：A total of 742 married nulliparous women（319 non-pregnant women and 423 pregnant women） seeking for eugenic care were enrolled.The concentration of anticardiolipin antibodies（ACA） was determined by the enzyme linked immunoabsorbent assay.Results：The ACA positive rate was 11.46%,12.06% for non-pregnant women and 11.11% for pregnant ones.The ACA positive rate for women with history of induced abortion was significantly higher than that of those without the history（P〈0.05）,and times of induced abortion had a positive relationship with the ACA positive rate.The ACA positive rate in women with one previous induced abortion within two years was significantly higher（P〈0.05）.Conclusion：Pregnancy isn＇t an impact factor of the ACA positive rate.While there is a close correlation between induced abortion and the occurrence of ACA.It is possible that ACA would gradually subside over time.