深圳市某街道2009-2010年手足口病病原体监测分析

Pathogenic surveillance and analysis of the hand,foot and mouth disease in a street of Shenzhen 2009-2010

目的对2009-2010年深圳市某街道手足口病进行病原学监测分析。方法收集5440份手足口病患者的病原学监测资料,对资料进行描述性分析和χ2检验。结果总肠道病毒(EV71和CoxA16)阳性率为43.3%,其中EV71阳性率为19.4%,CoxA16阳性率为23.9%,二者差异无统计学意义(χ2=0.396,P=0.529)。男性总肠道病毒阳性率为44.7%,女性阳性率为41.4%,不同性别间肠道病毒阳性率差异无统计学意义(χ2=0.076,P=0.783)。各年龄段肠道病毒阳性率差异有统计学意义(χ2=4.241,P=0.039)。12名重症患者中,EV71阳性率75.0%。结论深圳市某街道2009-2010年手足口病流行的病原体为EV71和CoxA16,不同性别的阳性率无差别,各年龄段肠道病毒阳性率差异有统计学意义。

Objective To analyze the etiology of the hand,foot and mouth disease（HFMD） in a street of Shenzhen,2009-2010.Methods 5 440 cases of pathogenic data of HFMD were collected and analyzed.Results Positive rate of pan-enterovirus was 43.3%.Positive rates of enterovirus 71 and coxsackie A16 were 19.4% and 23.9%,respectively,but the difference of positive rate of EV 71 and CoxA16 was not significant（χ2=0.396,P=0.529）.The male＇s positive rate of pan-enterovirus was 44.7%,and that of female was 41.4%,and their difference was not significant（χ2=0.076,P=0.783）.The difference of positive rate between different age groups was significant（χ2=4.241,P=0.039）.The positive rate of EV71 was 75.0% in 12 cases of severe patients.Conclusion EV71 and CoxA16 were the main pathogens of HFMD in a street of Shenzhen during 2009 to 2010,and the difference of positive rate was significant between different age group,but not significant between genders.