原发性膀胱印戒细胞癌1例报告并文献复习

Primary Signet-Ring Cell Carcinoma of Urinary Bladder:A Case Report and Review of the Literature

目的:探讨原发性膀胱印戒细胞癌的临床特征。方法:报告1例原发性膀胱印戒细胞癌患者的临床资料。患者因间歇性肉眼血尿就诊,术前检查未找到任何膀胱外病灶,行膀胱全切除术+输尿管造瘘术。结果:术后病检报告为膀胱印戒细胞癌。患者术后转肿瘤科化疗,目前正在随访中。结论:原发性膀胱SRCC非常罕见,进展快、恶性程度高,局部浸润性生长,有早期扩散转移倾向,预后差。其确诊主要依靠病理组织学检查。

Objective：To investigate the clinical features of primary signet-ring cell carcinoma of urinary blad der. Methods： A case for primary Signet-ring cell carcinoma of urinary bladder was reported. The patient complained of intermittently macroscopic hematuria. We could not find any lesions out of the urinary bladder from preoperative examinations, and cystectomy plus ureterostomy had been operated. Results：Signet-ring cell carcinoma of urinary bladder had been confirmed according to the pathological examination. The patient had been transferred to the department of Oncology for luther chemotherapy after operation and now is under follow-up. Conclusions： Sig net-ring cell carcinoma of urinary bladder has a series of characteristics such as extremely rare occurrence, fast development, highly malignant, local invasive growth , the trend of early pervasion and transfer,and poor prognosis. Histopathologic examination is the main way to confirm Signet-ring cell carcinoma of urinary bladder.