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TGF—β2及Myocilin蛋白在原发性开角型青光眼的研究进展 被引量:3

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摘要 转化生长因子-β2(transforming growth factor—β2,TGF—β2)是参与原发性开角型青光眼(primary open—angle glaucoma,POAG)发病机制的一个重要细胞因子,TGF—β2对小梁网的作用机制成为近年来研究的一个热点。Myoeilin是第一个被证明与POAG相关的基因,在许多眼内、眼外组织中均有表达,特别是小梁网。在过去的十几年里,学者们对Myocilin蛋白在正常眼或青光眼的功能方面做了很多的研究。此文将以TGF—β2对小梁网作用机制以及Myocilin蛋白在POAG发病机制中的研究为综述。
出处 《中国实用眼科杂志》 CSCD 北大核心 2011年第8期747-750,共4页 Chinese Journal of Practical Ophthalmology
基金 福建省自然科学基金(201001148)
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