两种不同术式治疗新生血管性青光眼的临床观察

Comparing clinical effect of two different methods in treatment of neovascular glaucoma

目的回顾性分析半导体二极管激光经巩膜睫状体光凝术（TSCPC）和睫状体冷凝术治疗新生血管性青光眼（NVG）的临床资料，评价两种不同术式的疗效。方法将50例（50只眼）NVG患者随机分为两组，TSCPC组26例（26只眼），睫状体冷凝组24例（24只眼）。结果对照组术后第1天眼压与本组术前相比差异无统计学意义（P〉0．05），第3天眼压明显下降，与本组术前相比差异具有统计学意义（P〈0．01）。TSCPC组术后第1天眼压明显下降，与本组术前相比差异具有统计学意义（P〈0．01）。术后两组同期眼压相比：第1d、3d、1周两组差异具有统计学意义（P〈0．01）；1月、3月、6月两组差异无统计学意义（P〉0．05）。TSCPC组术后早期疼痛时间短于对照组，差异有统计学意义（P〈0．01）。两组术后视力及治疗有效率差异无统计学意义（P〉0．05）。结论两种手术方法治疗NVG均有显著疗效。但相对于睫状体冷凝术TSCPC更安全、有效。

Objective To evaluate clinical effect of two different methods for the treatment of neovascular glaucoma （NVG） by analyzing data of diode laser transscleral cyclophotocoagulation （TSCPC） and cyclocryotherapy. Methods Fifty eyes of 50 patients with NVG were divided at random into two groups： 26 eyes treated by TSCPC （Test）, 24 eyes by cyclocryotherapy （Control）. Results There were no significant differences between postoperative IOP on 1st day and preoperative IOP in control group （P 〉0.05）, But there was a significant difference on 3rd day （P 〈0.01）. There was a significant difference in TSCPC group on 1st day （P 〈0.01）. Compared to the postoperative IOP of two groups during the same period, there was a significant difference on 1d, 3d, lw （P 〈0.01）, and there were no significant differences at lm, 3m, 6m （P 〉0.05）. The time of pain was shorter in TSCPC group （P 〈0.01）. There was no significant difference between the two groups in postoperative visual acuity and the operating efficiency （P 〉0.05）. Conclusions The two methods are effective for the treatment of NVG. However, TSCPC is an effective and safe method relatively.