期刊文献+

肾癌63例回顾性分析 被引量:8

下载PDF
导出
摘要 目的探讨肾癌的临床特点、诊疗措施以及预后的影响因素。方法回顾性分析我院1992年1月~2008年6月间收治的63例原发性肾癌的临床病理资料,分析肾癌的临床特点、诊疗措施,并探讨影响其预后的因素。结果男43例,女20例;年龄12~86岁,平均年龄为(51.6±3.6)岁。患者1年生存率为92.1%,3年生存率74.6%,5年生存率为58.7%。单因素分析表明,患者年龄(P=0.003)、肿瘤大小(P=0.034)、临床表现(P=0.010)、腔静脉癌栓(P=0.000)、TNM分期(P=0.000)、肿瘤病理类型(P=0.000)、淋巴转移(P=0.000)、远处转移(P=0.000)以及根治性手术(P=0.000)对肾癌预后具有显著性影响。Cox回归模型多因素分析表明,TNM分期(RR=2.473,95%CI 2.171~2.817,P=0.001)、淋巴转移(RR=3.153,95%CI 1.377~5.120,P=0.000)、远处转移(RR=3.618,95%CI 1.648~5.342,p=0.000)以及根治性手术(RR=3.955,95%CI 2.372~6.472,P=0.000)是影响肾癌预后的独立危险因素。结论肾癌根治术是首选治疗方法,患者术后预后较好。肾癌患者预后与肿瘤的TNM分期、是否行肾癌根治术、有无淋巴转移以及远处转移密切相关。
出处 《南方医科大学学报》 CAS CSCD 北大核心 2011年第8期1455-1457,共3页 Journal of Southern Medical University
  • 相关文献

参考文献9

  • 1董隽,石怀银,洪宝发,王晓雄.肾癌多灶性危险因素分析[J].中华泌尿外科杂志,2004,25(2):137-138. 被引量:3
  • 2Volpe A, Patard JJ. Prognostic factors in renal cell carcinoma [J]. World J Urol, 2010, 28(3): 319-27.
  • 3Licht MR, Novick AC, Goormastic M. Nephron sparing surgery in incidental versus suspected renal cell carcinoma [J]. J Urol, 1994, 152(1): 39-42.
  • 4Teloken PE, Thompson RH, Tickoo SK, et al. Prognostic impact of histological subtype on surgically treated localized renal cell carcinoma[J]. J Urol, 2009, 182(5): 2132-6.
  • 5郭三维,董柏君,黄翼然.肾癌预后分析的研究进展[J].国际泌尿系统杂志,2006,26(3):309-315. 被引量:12
  • 6李有元,胡志全,叶章群.肾细胞癌数据库三年临床资料COX模型分析[J].现代泌尿外科杂志,2008,13(4):294-296. 被引量:11
  • 7Sunela KL, Kataja MJ, Lehtinen ET, et al. Prognostic factors and long-term survival in renal cell cancer patients [J]. Stand J Urol Nephrol, 2009, 43(6): 454-60.
  • 8Frank I, Blute ML, Leibovich BC, et al. Independent validation of the 2002 American Joint Committee on cancer primary tumor classification for renal cell carcinoma using a large, single institution cohort[J]. J Urol, 2005, 173(6): 1889-92.
  • 9Kwon T, Song C, Hong JH, et al. Reassessment of renal cell carcinoma lymph node staging: analysis of patterns of progression IJl. Urology, 2011, 77(2): 373-8.

二级参考文献46

  • 1Bensalah K,Tostain J,Vincendeau S,et al.Prognostic significance of thrombocytosis in renal cell carcinoma.J Urol,2004,171:200,abstract 752.
  • 2Karim Bensalah,Emmanuelle Leray,Patricia Fergelot,et al.Guilléand Jean-Jacques Patard,Prognostic Value of Thrombocytosis in Renal Cell Carcinoma.The Journal of Urology,2006,175:859-863.
  • 3Steven C,Campbell.Prognostic Factors for Renal Cell Carcinoma:Integrating Laboratory and Molecular Factors.The Journal of Urology,2006,175:813-814.
  • 4Motzer R J,Bacik J,Schwartz LH,et al.Prognostic factors for survival in previously treated patients with metastatic renal cell carcinoma.J Clin Oncol,2004,22:454-63.
  • 5Robert J,Motzer,Jennifer Bacik,et al.Madhu Mazumdar.Prognostic Factors for Survival of Patients with Stage Ⅳ Renal Cell Carcinoma:Memorial Sloan-Kettering Cancer Center Experience.Clinical Cancer Research,2004,10:6302-6303.
  • 6Ronald M,Bukowski,Sylvie Negrier,et al.Prognostic Factors in Patients with Advanced Renal Cell Carcinoma:Development of an International Kidney Cancer Working Group.Clinical Cancer Research,2004,0:6310-6314.
  • 7Atkins M,McDermott D,Mier J,et al.Carbonic anhydrase Ⅸ(CAIX) expression predicts for renal cell cancer (RCC) patient response and survival to IL-2 therapy.Proc Am Soc Clin Oncol,2004,23:383,abstract 4512.
  • 8Kim HL,Seligson D,Liu X,et al.Using protein expressions to predict survival in clear cell renal carcinoma.Clin Cancer Res,2004,10:5464.
  • 9Thompson RH,Gillett MD,Cheville JC,et al.Costimulatory B7-H1in renal cell carcinoma patients:indicator of tumor aggressiveness and potential therapeutic target.Proc Natl Acad Sci USA,2004,101:17174-17179.
  • 10Brian R,Lane,Michael W,et al.Predicting outcomes in renal cell carcinoma.Current Opinion in Urolog,2005,15:289-297.

共引文献22

同被引文献69

  • 1曹军,申余勇,程伟,陈琦.影响肾癌患者预后的因素分析[J].陕西医学杂志,2008,37(12):1599-1601. 被引量:4
  • 2方祖军,燕翔,郑捷,杨醌,陈波,姚孟树,丁强,张元芳.肾癌的病理类型与预后的关系[J].临床泌尿外科杂志,2006,21(4):262-263. 被引量:22
  • 3Lewis G,Maxwell AP. Early diagnosis improves survival in kidney cancer[J]. Practitioner, 2012,256 ( 1748 ) : 13-16,12.
  • 4Major JM,Pollak MN ,Snyder K,et al. Insulin-like growth factors and risk of kidney cancer in men[J]. Br J Cancer, 2010,103 ( 1 ) : 132-135.
  • 5Chow WH, Dong LM ,Devesa SS. Epidemiology and risk factors for kidney cancer[J]. Nat Rev Urol, 2010,7 (5) : 245-257.
  • 6Smaldone MC ,Uzzo RG. Kidney cancer in 2011: Objectifying risk for localized renal masses[J]. Nat Rev Urol,2012,9(2):70-72.
  • 7Klipfel J, Jacobson T M, Havel M. Radical nephrectomy with inferior vena cava (IVC) thrombectomy: implications for post - operativenursing care [J ]. Urol Nurs, 2010, 30 (6) : 347.
  • 8Bourdeanu L, Twardowski P, Pal S K. Nursing considera- tions with pazopanib therapy: focus on metastatic renal cell carcinoma[J]. Clin J Oncol Nuts, 2011, 15(5) : 513.
  • 9Smaldone MC,Uzzo RG. Kidney cancer in 2011 : Objectifying risk for localized renal masses[ J ]. Nat Rev Uro1,2012,9 (2) :70 - 72.
  • 10Oncologic Long-term Outcome of Elective Nephron-sparing Surgery Versus Radical Nephrectomy in Patients With Renal Cell Carcinoma Stage pT1b or Greater in a Matched-pair Cohort[J]. Urology . 2011 (4)

引证文献8

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部