高血压脑出血止血与再出血机制探讨及扩血管剂之影响

Mechanism ofstopping bleeding and rebleedingin hypertensivebrain hemorrhage,as wellasinfluence of vasodilator

为了解扩血管药对脑出血止血和再出血的发生之影响是有利还是有害。采用硝普钠应用后止血时间之变化和止血后再出血发生率的变化；罂粟硷在血管吻合口和血管横断口局部应用对再出血的影响；血压升高对出血部位止血后再出血的影响等实验。结果：扩血管药对已止血处不增加再出血，且全身应用此类药之综合作用有利于防止脑出血扩大和再出血；血压升高是脑出血加剧和再发的危险相关因素；扩血管药对血管侧向破口出血不增加再出血，而高血压脑出血恰巧为此类型出血。结果提示扩血管药物在高血压脑出血的适当时机可以应用，并有利于脑功能的恢复。

Objective: To find out relation between vasodilator and rebleeding, stopping bleeding-Methods: 1-Animalexperiment: Vasodilator and bleeding ,rebleeding,stop bleeding;rising of blood pressure (BP) and re bleeding-2-Clinicalexperiment and review of periodicals-Results: Hypertension causes rebleeding,but vasodilatornot-Conclusion: On the right moment vasodilator may be used for hypertensive brain bleeding-The drug is favourablefor brain-