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2型糖尿病患者尿N-乙酰-β—D一氨基糖苷酶和尿微量白蛋白联合检测在早期肾损伤诊断中的价值 被引量:2

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摘要 目的探讨尿N-乙酰-β-D-氨基糖苷酶(尿NAG)、尿微量白蛋白(尿MAlb)对2型糖尿病早期肾损伤的诊断价值。方法2型糖尿病组60例,正常X,JN组30名,分别用速率法和免疫透射比浊法检测尿NAG、尿Malb。结果糖尿病组尿NAG20.14±13.3U/L、尿MAlb39.8±33.Img/L,对照组分别为5.34±1.2U/L、4.4±2.3mg/L,糖尿病高组于正常对照组3~9倍,,检验差别有高度统计意义(P〈0.01);糖尿病组尿NAG阳性率88.3%、尿MA|b81.6%,X^2检验差异无显著性(P〉0.05);两两比较尿NAG、尿MAIb各自灵敏度100%、90.7%;特异性87.8%、100%;准确性均为94.4%。结论尿NAG、尿MAIb联合检测可提高糖尿病早期肾损伤诊断的敏感性与特异性。
作者 钮丽萍 沈昊
出处 《中国血液流变学杂志》 CAS 2011年第2期349-349,353,共2页 Chinese Journal of Hemorheology
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