睡眠呼吸综合征患者动态心电图指标分析

Analysis on the Ambulatory Electrocardiogram in the Patients with Sleep Apnea Syndrome

目的通过动态心电图(AECG)研究睡眠呼吸暂停综合征(SAS)患者缺血负荷(TIB)、心律失常、心率变异(HRV)等指标的变化及其临床意义。方法选择因睡眠打鼾及有窒息感就医的患者354例,在行多导睡眠图(PSG)检查同时行AECG记录。根据PSG结果分为SAS组和非SAS组,对所得数据进行分析。结果经PSG确诊的SAS患者255例中发生TIB的177例,心律失常213例;非SAS患者99例,发生TIB患者9例,心律失常21例,差异有统计学意义(P<0.05)。SAS组较非SAS组HRV明显降低(P<0.05)。结论 SAS是临床引发TIB、心律失常的重要因素,HRV是SAS敏感指标之一。

Objective To investigate the changes and clinical significance of ambulatory electrocardiogram parameters in the patients with sleep apnea syndrome （SAS）. Methods The 354 patients who were admitted in hospital due to snoring or suffocated feeling when sleeping were enrolled. The patients were examined by polysomnography combining ambulatory electrocardiogram. And the patients were divided into two groups according to the report of polysomnography： SAS group （255 patients） and non-SAS group （99 patients）. Results The total ischemia burden （TIB） was detected in 177 patients and arrhythmia 213 patients in SAS group, which were significantly higher than those in non-SAS group （P〈0.05）. The patients in SAS group showed reduced heart rate variance （HRV） than those in non-SAS group （P〈0.05）. Conclusion Sleep apnea syndrome is an important factor for total ischemia burden and arrhythmia in patients. HRV is a quite sensitive parameter.