112例TIA患者预后及其危险因素的分析

TIA patient's prognosis and analysis of risk factors

目的:分析短暂性脑缺血发作(TIA)患者发病后3个月的预后及其与各种危险因素的相关性。方法:对112例临床确诊为TIA患者的3个月随访及相关危险因素的资料进行分析;并对其临床资料和头颅MR弥散加权成像(DWI)异常及正常患者的预后进行比较。结果:DWI检查异常者血管事件发生率为80.0%,正常者发生率为3.7%,二者预后的比较差异有统计学意义(P<0.001)。随着年龄的增长,TIA患者发生梗死的几率逐渐增加,且颅内动脉狭窄程度越重,梗死的几率越大。危险因素高血压、糖尿病与无危险因素比较,梗死几率明显升高。颈内动脉系统TIA组与椎基底动脉系统TIA组预后构成不同(P<0.05)。结论:TIA是脑梗死的重要危险因素。积极控制高血压、糖尿病和降血脂稳定斑块对改善脑血管病的预后具有重要意义。

Objective：To analyses transient ischemic attack（TIA） patients after 3 months of the prognosis of various risk factors and its relevance.Methods：clinical diagnosis of 112 cases of patients for TIA 3 month’s follow-up and associated risk factors analysis of data;and their clinical material and heads of weighted imaging（DWI MR diffuse） anomalies and normal patient’s prognosis are compared.Results： incidence of abnormal vascular events DWI check for normal incidence 80.0% 3.7% and the prognosis of comparative differences,both are statistically significant（P〈0.001）.As the growth of the age,TIA patients occurring gradually increased risk of mi and intracranial artery stenosis degree is heavier,the risk of mi.Risk factors for high blood pressure,diabetes and no risk factors comparison,infarction significantly higher risk.Internal carotid artery system with vertebrobasilar artery of TIA prognostic constitute a different system TIA group（P〈0.05）.Conclusions： TIA is an important risk factor for cerebral infarction.Positive control high blood pressure,diabetes and lipid-lowering stability to improve the patch cerebrovascular disease prognosis is of great significance.