脑裂头蚴病的影像学特征分析

Imaging Characteristics of Cerebral Sparganosis

目的研究脑裂头蚴病的CT和MR特点,以提高本病的影像学诊断水平。方法回顾性分析11例确诊为脑裂头蚴病患者的临床、CT和MR资料。11例均行CT检查,其中10例行MR检查。结果 11例均可见脑白质水肿和变性,CT表现特点为低密度灶伴"针尖"样钙化,MRI表现特点为串珠、扭曲条索、"隧道"样增强。4例术前随访中发现病灶位置改变,7例血清免疫学检查显示裂头蚴抗体阳性。11例中9例在CT定位下行立体定向活检,2例行开颅手术取出。结论脑裂头蚴病具有明显的影像学特征,如"针尖"样钙化、串珠、扭曲条索、"隧道"样增强及游走性,结合临床资料和血清免疫学检查诊断并不困难。

Objective To study the CT and MR features of cerebral sparganosis so as to improve the accuracy of imaging diagnosis.Methods Clinical,CT and MR findings were retrospectively analyzed in 11 patients with cerebral sparganosis.All patients underwent CT scan,and 10 patients underwent MR scan.Results The degeneration and edema of cerebral white matter were found in all patients.CT showed low-density lesions with punctate calcifications.MRI showed bead-shaped,tortuous cordlike images and tunnel sign enhancement.At preoperative follow-up examination,lesion location changed in 4 patients.Enzyme linked immunosorbent assay for antisparganum antibody was positive in 7 patients.Among the 11 cases,9 underwent CT-guided stereotactic biopsy and 2 underwent craniotomy for surgical removal of lesions.Conclusion Cerabral sparganosis has typical imaging characteristics,such as punctuate calcifications,bead shaped and tortuous cordlike images,and tunnel sign enhancement.Combined analysis of clinical data and immunological examination is effective for definitive diagnosis of cerebral sparganosis.