陕西汉中盆地63例甲型H1N1流感病例流行病学和临床学分析

Analysis of epidemiological and clinical characteristics of 63 confirmed cases of influenza A(H1N1) in Hanzhong city of shangxi province

目的探讨甲型H1N1流感的流行病学和临床学特点。方法对我院收治确诊的63例甲型H1N1流感患者的流行病学资料,临床资料进行分析研究。结果发病年龄主要集中在6~22岁的少年儿童及青年学生中,占94%（59/63）。主要临床表现为发热、咳嗽、咳痰、咽痛等流感样症状,实验室检测,外周白细胞减少或正常者居多,淋巴细胞多升高。部分患者心肌酶、肝酶轻度升高,个别心律不齐,ST改变,热退后出现窦缓,有占19%的患者胸部X线有炎症改变。结论甲型H1N1流感传染性强,传播速度快,易引起暴发流行,临床症状较轻,在一般对症治疗同时给予抗病毒中药或奥司他韦治疗均能获得较好疗效。

Objective To discuss the epidemiological and clinical characteristics of influenza A（H1N1）.Methods The clinical data of 63 confirmed cases of influenza A（H1N1） from october to december were analyzed retrospectively.Results Many travellers had returned before the Influenza outbreaked.The first three Patients came from different infectous focus.The mean age of onset is 15.7 years old（6-68 years）,concentrating mainly in the children and younth strdents from 6 years to 22 years,（94%,59/63）.The main symptoms were influenza-like symptoms including fever cough expectoration and sore throat.The number of leukocytes in the peripheral blood was normal or low.Lymphocyte count was high in many cases.Part patients showed that the myocardical enzyme and Liver enzyme increased transiently few,patients showed cardical arrhythmia,ST altering,sinus bradycardia after fever.Some patients（19%） had the inflammatory change of chestx-Line.Conclusions The infectivity of the Influenza A（H1N1） is high.It can spread in high speed.and lead to influenza pandemic.The symptoms are slight.At the meanwhile of symptomatic treatment,the treatment of the antiviral traditional medicine or oseltamivir can get perferably curative effect.Patients with complication should be treated with antiinfection,protecting cardiac muscle in early stage,preventing pronunciation is also very important.We should strengthen the management of the floating population.Actively carry out the Vaccination of influenza A（H1N1）,rise.the crowds immunization barrier,block up transmission.