不同年龄组慢性阻塞性肺病患者急性加重期痰培养结果比较

Comparison of sputum culture in patients with AECOPD in different age

目的探讨不同年龄组慢性阻塞性肺病患者急性加重期痰培养结果的差异。方法收集2008年8月至2010年8月间安庆市立医院呼吸科收治的慢性阻塞性肺病患者急性加重期患者,依据三个年龄段分为三组：A组：小于65岁,B组：65~75岁,C组：75~85岁。入院后未使用抗生素之前对患者行痰培养,比较三组患者之间痰培养的差异。结果 A组患者痰培养阳性率19.0%,多重耐药菌阳性率3.4%;B组患者痰培养阳性率39.0%,多重耐药菌阳性率14.1%;C组患者痰培养阳性率62.1%,多重耐药菌阳性率27.3%。三组患者之间痰培养阳性率（P〈0.05）多重耐药阳性率（P〈0.05）差异有统计学意义。结论慢性阻塞性肺病患者急性加重期痰培养阳性率及多重耐药菌阳性率随年龄增长而升高。

Objective Investigate the comparison of sputum culture in patients with AECOPD in different age.Method Patients with AECOPD admitted into Anhui provincial AnQing municipal hospital from August,2008 to August,2010 were collected and stratified into three groups according to the age：Group A： Younger than 65 years old,Group B： 65-75 years old,Group C： 75-85 years old.Positive rate of sputum culture was compared among three groups before the application of antibiotics.Result Positive sputum culture rate of Group A is 19.0%,multi-drug resistance rate of Group A is 3.4%;positive sputum culture rate of Group B is 39.0%,multi-drug resistance rate of Group B is 14.1%;positive sputum culture rate of Group C is 62.1%,multi-drug resistance rate of Group C is 27.3%;There is statistical difference among the positive sputum culture rate（P0.005）and multi-drug resistance rate（P0.005） of three groups.Conclusion The older the age,the higher the positive rate and multi-drug resistance rate of sputum culture in patients with AECOPD.