成人和儿童纤维支气管镜治疗支气管结核病的初步疗效比较

Compare the value of bronchofiberoscope in the treatment of endobronchial tuberculosis(EBTB) between children and adult

目的比较成人和儿童纤维支气管镜治疗支气管结核病(EBTB)的初步疗效。方法 46例确诊的EBTB分为全身化疗+成人纤支镜局部治疗组(A组)和全身化疗+儿童纤支镜局部治疗组(A组),A组和B组均为23例。结果根据临床表现、胸部X片检查、支气管镜检查、痰检评价疗效A组和B组的有效率分别为69.6%和95.7%(P=0.047)、78.3%和100%(P=0.047)、73.9%和95.7%(P=0.096)、87.0%和91.3%(P=0.665)。结论联合全身化疗和儿童支气管镜内给药治疗EBTB的疗效、患者耐受性和可行性均较好。

Objective To compare the value of bronchofiberoscope in the treatment of endobronchial tuberculosis（EBTB） between children and adult.Methods 46 patients with biopsy-proven EBTB were divided into A group（23 child patients） and B group（23 adult patients）.In addition to regular anti-tuberculosis chemotherapy,all patients were treated by bronchofiberoscope.Results To value the total 1 effective rate by clinical symptoms,X-ray film,bronchofiberoscope and sputum examination.The total effective rate between A group and B group was 69.6% and 95.7%（P=0.047）,78.3% and 100%（P=0.047）,73.9% and 95.7%（P=0.096）,87.0% and 91.3%（P=0.665） respectively.Conclusion The curative effect of comprehensive treatment on EBTB through bronchofiberoscope is definite,it is feasible and simple in children.