以微生物代谢物进行除草剂开发的研究进展

Progress on the Study of Herbicides Sourced from Microbiological Metabolites

概述了以微生物代谢产物进行除草剂研究的主要方向,即以下5个方面:筛选微生物从中分离具有除草活性的新化合物;对高除草活性的微生物菌株的市场化研究;对微生物源高活性化合物的全合成或结构改造;对微生物源除草活性系列化合物的构效关系研究;对天然除草活性化合物的作用机制研究。这些研究表明,以微生物代谢物进行除草剂的研究仍将是除草剂开发的一个重要热点。

The study in herbicides sourced from microbiological metabolites mostly focus on the following aspects： screening new herbicidal active compounds from the microorganisms;increasing the products yield from fermentation to decrease the cost;total synthesis or modification of the active compounds;QSAR of the analogues,and the mechanism of the active metabolites.All the studies indicate that the research on the herbicides from microbiological metabolites is still a hot spot in herbicide research area.