胸腔镜与传统手术对非小细胞肺癌远期疗效的影响

Long-term Outcome of Video-assisted Thoracic Surgery versus Traditional Thoracotomy for Non-small Cell Lung Cancer

目的分析胸腔镜手术治疗中早期非小细胞肺癌(NSCLC)的远期疗效。方法回顾性分析131例NSCLS患者的临床资料,按治疗方法的不同分成VATS组和S组,VATS进行胸腔镜手术,S组进行传统开胸手术,分析两组5年生存期。结果 VATS较S组手术时间长、术中出血量少、留置胸管时间短、术后止痛时间短、术后住院时间短,差异有统计学意义(P<0.01),而清扫淋巴结个数差异无统计学意义(P>0.05);两组5年生存率差异无统计学意义(P>0.05)。结论 VATS手术时间较传统开胸手术时间长,但其对患者手术损伤较小,缩短术后恢复时间及住院时间,提高患者生活质量,但不能提高中早期NSCLC患者的5年生存期。

Objective To explore the long-time outcomes of video-assisted thoracoscopic surgery（VATS）in patients with clinically resectable non-small cell lung cancer（NSCLC）.Methods 131 patients with proven stages NSCLC underwent VATS（VATS group）or traditional thoracotomy surgery（S group）major pulmonary resection.The 5-year survival rates were compared between the two groups.Results Compared with S group,the mean operative time was longer,the bleeding loss,chest tube lien time,postoperative pain time were shorter in VATS group（P0.01）.Besides,the number of lymph node dissection was not significantly different between the two groups（P0.05）.The overall 5-year survival was not significantly different between the two groups（P0.05）.Conclusion Compared with traditional thoracotomy,VATS has longer operation time but shorter recovery time and hospitalization time in patients with clinically resectable NSCLC.VATS can improve the quality of patients＇ life but prolong survival 5-year survival period.