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Red blood cell level is increased in obese but not in non-obese patients with coronary heart disease

Red blood cell level is increased in obese but not in non-obese patients with coronary heart disease
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摘要 目的将与冠的心疾病(CHD ) 和它的临床的意义在肥胖、非肥胖的病人检验红血房间层次的变化。冠的心疾病的 230 个盒子被选择并且划分了成肥胖的组和 nonobese 组的方法。肥胖和非肥胖基于身体团索引被定义(BMI 我(Y) 28.0kg/m2 ) ,或腰臀部比率(男人 > 0.9,女人 > 0.85 ) 。另外, 130 个健康对象作为控制被招募。冠的损害的病理学的地位是根据冠的脉管的图象分割评估标准(美国心协会 1984 ) 和 Gensini 得分系统分析的份量上。血红素层次和红血房间的变化的结果在肥胖的组,数有 CHD 的 nonobese 组和控制组被比较。而且, Multivariant 逻辑回归分析被使用估计在红血房间和冠的动脉疾病之间的关联。结果红血房间计数和在有 CHD 的肥胖的组的血红素的水平在有 CHD 的非肥胖的组比那高[(4. Objective To examine the changes of red blood cell levels in the obese and non-obese patients with coronary heart disease (CHD) and its clinical significance. Methods 230 cases of coronary heart disease were selected and divided into the obese group and the non- obese group. Obesity and non-obesity were defined based on the body mass index (BMI if 28.0kg/m2), or waist-hip ratio (men〉 0.9, women〉 0.85). In addition, 130 healthy subjects were recruited as controls. The pathological status of coronary lesions was quantita- tively analyzed according to the Coronary Vascular Image Segmentation Evaluation Criteria (American Heart Association 1984) and the Gensini scoring system. Results of the changes of both the hemoglobin levels and the red blood cell count in the obese group, the non- obese group with CHD and the control group were compared. Besides, Multivariant Logistic Regression Analysis was applied to assess the correlation between the red blood cells and the coronary artery disease. Results The red blood cell count and the level of hemoglobin in the obese group with CHD was higher than that in the non-obese group with CHD [(4.35 ± 0,55) and (4.13 ± 0.56) 10^9/L; (136.71± 15.87) and (129.96 ±16.23) g/L, P 〈 0.05 in both]; the proportion of acute coronary syndrome in the obese group with CHD was higher in the obese group with CI-/D than that in the non-obese group with CHD (P〈0.05); Multivariant logistic regression analysis also showed that the red blood cell count was positively correlated with obesity with CHD.Conclusion The red blood cell count and the level of hemoglobin in the obese group were higher than those in the non-obese group; the increase of red blood cell count and hemoglobin level is one of the independent risk factors for the obese patients with CHD.
出处 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2010年第3期143-146,共4页 老年心脏病学杂志(英文版)
关键词 冠心病 细胞水平 logistic回归分析 肥胖 患者 冠状动脉疾病 红细胞计数 急性冠脉综合征 coronary heart disease red blood cell hemoglobin obesity
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