大肠杆菌内毒素对肉鸡腹水症的影响

EFFECTS OF E.COLI (O_(111)B_4) ENDOTOXIN ON ASCITE IN BROILERS

试验选用１日龄商品肉鸡５０只，随机分成对照组２０只，试验组３０只。从第４周龄起，试验组肉鸡腹腔注射大肠杆菌内毒素（８ｍｇ／ｋｇ／只），每周攻毒一次，共３次，每次攻毒后第７ｄ称重，宰杀对照组５只，试验组１０只以供检测．试验结果如下：大肠杆菌内毒素（０(１１１）Ｂ４）对肉鸡心，肝造成明显的病理变化，随着攻毒次数的增多，心脏病变种类由２种增加到４、５种，肝脏病变种类由２种增加到３、４种，以心脏的病变更为明显。攻毒组的肉鸡腹水症发生率为１０％，高于对照组（６．６７％）；心扩张发生率为１６．６７％，高于对照组（１３．３３％）。但统计学分析差异不显著（Ｐ＞０．０５）。可见，大肠杆菌内毒素有促进腹水症发生增高的趋势，但不是导致肉鸡发生腹水症的主要致病因素。

50 one-day broilers were individed randomly into control group (20) and test group (30). The broilers in test group were injected abdominally with E.coli endotoxin (8mg/kg), once per week at 4,5 and 6 weeks age. Results showed as follows: there were apparently pathology changes for heart and liver of broilers in test group, the categories of pathology changes of broilers in test group was in heart than in liver at 4,5 and 6 weeks. Test group which was injected with E.coli endotoxin showed less significantly RVH (right ventricular hypertrophy)(16.67%) and Ascite(10%) than control group which showed RVH(6.67%) and Ascite (13.33%),there were tendency to gradually increase Ascite in test group, but results indicated that E.coli.endotoxin was not one of main pathogenic factors.