不同浓度肝素封管液在小儿静脉留置针封管中的应用

Effect of heparin sodium solution of different concentration in sealing up the tube of intravenous indwelling needle in children

目的观察3种不同浓度肝素钠封管液用于小儿静脉留置针封管的效果。方法选择需静脉留置针输液的患儿120例,随机分成3组,每组40例,A、B、C3组分别采用生理盐水100、250、500mL+肝素12500U作为封管液,比较3组留置针的留置时间、堵管发生率、并发症的发生情况。结果 B组平均留置时间比A组长,而A组平均留置时间比C组长,而堵管发生率A组略低于B组,而C组则明显高于B组,差异有统计学意义(P<0.05)。而3组的并发症无明显差异(P>0.05)。结论生理盐水250mL+肝素12500U作封管液用于小儿静脉留置针封管的疗效最佳,值得临床推广。

Objective To observe the effect of heparin sodium solution in three different concentrations used to seal up the tube of intravenous indwelling needle in children. Methods 120 cases of patients who required intravenous indwelling needle were randomly divided into three groups which namely A, B and C groups, 40 cases respectively.A,B and C groups were sealed up the tube of intravenous indwelling needle with heparin sodium 12 500 U add in normal sodium 100 mL, 250 mL and 500 mL.Comparisons of the retention time, ratio of blocking up and applications among the three groups were performed. Results Retention time of tube in B group was longer than A group,and A group was longer than C group.Ratio of blocking up tube in A was a little lower than C group,and C group was abviously higher than B group.All above were showed statistical significance（ P 0.05）.The applications of tube were showed no statistical significance among the three groups（ P 0.05）. Conclusion Heparin sodium 12 500 U add in normal sodium 250 mL may be the best to seal up the tube of intravenous indwelling needle in children.