摘要
目的探讨糖尿病前期(IGR)患者左心室功能的改变。方法应用超声心动图检测40例糖耐量正常者(NGT)及40例IGR患者的左心室收缩功能指标(EF、FS、Sa、SRs)、舒张功能指标(E、A、E/A、Ea、Aa、Ea/Aa、SRe、SRa)及Tei指数。结果①与NGT组相比,IGR组收缩功能指标Sa及SRs降低(P<0.05),EF和FS的改变无统计学意义;②IGR组舒张功能指标Ea、SRe、SRe/SRa及Ea/Aa显著降低(P<0.01或P<0.05),而E、A、E/A、Aa和SRa在两组间无显著性差异。③IGR组Tei指数明显増高(P<0.05)。结论 IGR患者已有左室功能受损,超声心动图检测可早期发现糖尿病前期患者的左室功能损害。
Objective To study the changes of left ventricular function in patients with prediabetes ( IGR ). Methods Left ventricular contractive function index ( EF, FS, Sa, SRs ), relaxant function index ( E, A, E/A, Ea, Aa, Ea/Aa, Sre, SRa ) and Tel-index in all patients of ]GR group ( 40eases ) and normal glucose tolerance ( NGT ) group ( 40cases ) were measured by echocardiograph. Results (1) Compared with NGT group, systolic function parameters ( Sa and SRs ) in IGR group were lower (P 〈 0.05 ), but no differences in EF and FS; (2) Diastolic function parameters ( Ea, SRE, SRe/SRa ) and Ea/Aa in IGR group were significantly lower ( P 〈 0.01or P 〈 0.05 ), but no differences in E, A, E/A, Aa and SRa; (3) Tei-index was significantly higher in IGR group ( P 〈 0.05 ). Conclusion Left ventrivular function is impaired in patients with prediabetes. The changes of left ventrivular function can be shown hy echocardiography early.
出处
《中国现代医生》
2011年第23期70-71,77,共3页
China Modern Doctor
关键词
糖尿病前期
左心室功能
超声心动图
Prediabetes
Left ventricular function
Echocardiograph