脐火疗法联合单重血浆置换术治疗慢性重型肝炎

Effect of Qihuo Therapy Combine with Artificial Liver on Chronic Severe Hepatitis

目的:观察脐火疗法联合人工肝治疗慢性重型肝炎的疗效。方法:38例重型肝炎患者随机分为2组,对照组18例为常规内科对症支持基础上应用单重血浆置换术治疗;治疗组20例在对照组治疗基础上加用脐火疗法,疗程均为14 d。结果:治疗组患者脘腹胀满、乏力、口苦、畏寒症状改善明显,与对照组比较有显著性差异(P<0.05),两组均明显降低患者胆红素水平,治疗组疗前总胆红素为(435.4±182.2)μg.L-1,治疗后降为(65.7±22.0)μg.L-1,对照组疗前总胆红素为(422.7±178.5)μg.L-1,治疗后降为(98.7±36.1)μg.L-1,但治疗组较对照组改善更为显著(P<0.05),两组在改善患者肝功能方面无显著差异。结论:脐火疗法可明显提高人工肝治疗效果,未见不良反应。

Objective： To observe the effect of Qihuo Therapy combine with artificial liver.On chronic severe hepatitis patients.Method： Thirty-eight patients with chronic severe hepatitis were randomly divided into 2 groups.The eighteen cases in control group were based on conventional medical treatment and supportive liver application on the basis of a single heavy plasma exchange treatment,on the basis of conventional therapy,twenty patients in the treated group were treated with Qihuo therapy every other day after artificial liver therapy,the therapeutic course for both groups was 14 days.Before and after treatment,and the changes of liver function,intestinal endotoxemia and patients＇subjective symptoms were observed.Result： The patients in the treated group abdominal distention,fatigue,mouth pain,chills improved significantly,compared with the control group there were significant differences（P 0.05）,significantly decreased in both groups of patients and bilirubin endotoxin levels,improve blood clotting function,but the treated group improved more significantly（P 0.05）,liver function in both groups was no significant difference.Conclusion： Qihuo therapy is an effective technique which can improve the artificial liver effect on chronic severe hepatitis,and with no adverse reaction.