期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

子宫内膜异位症患者血清中单核细胞趋化蛋白-1水平变化及意义 被引量：4

下载PDF
导出
摘要 子宫内膜异位症（EM）是育龄女性的常见疾病，也是常见不孕症原因。EM的发病机制还不明确，至今已提出多种理论，如经血逆流学说、体腔上皮化生学说及血液淋巴播散学说。而这些学说均不能完整解释该病的发病原因。单核细胞趋化蛋白-1（MCP-1）是一种对单核细胞具有特异性趋化及激活活性的细胞因子，是吸引单核细胞浸润到肿瘤及组织中的有效介质。近年来MCP-1在EM发病机制中的作用越来越受到重视。本文将通过对EM患者血清中MCP-1的测定，探讨MCP-1与EM的关系。
作者 王俊然 郑素琴 郭小明
机构地区 河北省唐山市妇幼保健院病理科 河北联合大学基础医学院病理学教研室 河北省唐山市妇幼保健院产科
出处 《河北医药》 CAS 2011年第16期2447-2448,共2页 Hebei Medical Journal
关键词 子宫内膜异位症 单核细胞趋化蛋白-1
分类号 R711.71 [医药卫生—妇产科学]
  • 相关文献

参考文献5

  • 1郭小明,王俊然.单核细胞趋化蛋白-1与子宫内膜异位症相关性研究[J].河北医药,2010,32(19):2722-2723. 被引量：5
  • 2Yih S, Katabuchi H, Araki M, et al. Expression of monocyte ehemoat tractant protein-1 in peritoneal indometriotie cells. Virchows Arch, 2001, 438:70-77.
  • 3Akoum A, Lemay A, McColl S, et al. Elevated concentration and biologic activity of monocyte chemotactic protein-1 in the peritoneal fluid of patients with endometriosis. Fertil Steril, 1996,66 : 17-23.
  • 4Arici A, Oral E, Attar E, et al. Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endomctriosis and its modulation of expression in mesothelial cells. Fcrtil Steril, 1997,67 : 1065-1072.
  • 5Akoum A, Lemay A, McColl SR, et al. Increased monocyte chemotactic protein-1 level and activity in the pefiphera 1 blood of women with endometriosis. Am J obstet Gynecol, 1996,66 : 175-176.

二级参考文献6

  • 1American society for reproduction medicine.Revised American Society for Reproductive MediCine classincation of endometriosis 1996.Fetil Steril,1997,67:817-821.
  • 2Mrata M,Arata S,Nose K.Involement of reactive oxygen spesis in the induction of chemokine JE?MCP-1 gene by phobol-12-myristate -13-acetate in Balb 3T3 cells.Cell Struct Funct,1997,22:231-238.
  • 3Yih S,Katabuchi H,Araki M,et al.Expression of monocyte chemoat tractant protein-1 in peritoneal indometriotic cells.Virchows Arch,2001,438:70-77.
  • 4Akoum A,Lemay A,McColl S,et al.Elevated concen tration and biologic activity of monocyte chemotactic protein-1 in the peritoneal fluid of patients with endometriosis.Fertil Steril,1996,66:17-23.
  • 5Arici A,Oral E,Attar E,et al.Monocyte chemotactic prote in-1concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells.Fertil Steril,1997,67:1065-1072.
  • 6Akoum A,Lemay A,McColl SR,et al.Increased monocyte chemotactic protein-1 level and activity in the periphera l blood of women with endometriosis.Am J obstet Gynecol,1996,66:175-176.

共引文献4

同被引文献29

  • 1李红,王永来,王冬梅,陈英汉.子宫内膜异位症患者腹腔液及异位内膜组织中单核细胞趋化蛋白-1水平与疾病发生关系的研究[J].中国实用妇科与产科杂志,2005,21(1):47-48. 被引量：2
  • 2Iwata H, Okumura Y, Seishima M et al. Overexpression of monocyte chemoattractant protein - 1 in the overlying epidermis of multicentric reticulohistiocytosis lesions: a case report [J]. Int J Dermatol, 2012, 51 (4) : 492.
  • 3Lin HH, Liao C J, Lee YC et al. Lipocalin -2- induced cy- tokine production enhances endomctrial carcinoma cell survival and migration [J]. Int J Biol Sci, 2011, 7 (1) : 74.
  • 4Bersinger N A, H Dechaud, B McKinnon, et al. Analysis of cytokincs in the peritoneal fluid of endometriosis pa- tients as a function of the menstrual cycle stage using the Bio-Plex(R) platform[ J]. Arch Physiol Biochem, 2012 (118) : 210 -218.
  • 5Tao Y, Q Zhang, W Huang, et al. The peritoneal leptin, MCP-1 and TNF-alpha in the pathogenesis of endometrio- sis-associated infertility [ J ]. Am J Reprod Immunol, 2011(65) 403 -406.
  • 6Khan K N, M Kitajima, K Hiraki, et al. Immunopatho- genesis of pelvic endometriosis : role of hepatocyte growth factor, macrophages and ovarian steroids [ J ]. Am J Re- prod Immunol, 2008(60): 383-404.
  • 7Abangan R S, Jr C R Williams, M Mehrotra, et al. MCP1 directs trafficking of hematopoietic stem cell-de- riv, ed fibroblast precursors in solid tumor [ J ]. Am J Pathol, 2010(176) : 1914 - 1926.
  • 8Conductier G, N Blondeau, A Guyon, et al. The role of monocyte chemoattractmit protein MCP1/CCL2 in neuroin- flammatory diseases[ J ]. J Neuroimmunol, 2010 (224) : 93 - 100.
  • 9Bacci M, A Capobianco, A Monno, et al. Macrophages are alternatively activated in patients with endometriosis and required for growth and vaseularization of lesions in a mouse model of disease[ J]. Am J Pathol, 2009 ( 175 ) : 547 - 556.
  • 10Wilson T J, K C Nannurn, M Futakuehi, et al. Cathep- sin G-mediated enhanced TGF-beta signaling promotes an- giogenesis via upregnlation of VEGF and MCP-1 [ J ]. Cancer Lett, 2010(288) : 162 - 169.

引证文献4

二级引证文献13

河北医药
2011年 第16期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部