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地佐辛抑制阑尾牵拉反射的作用 被引量:7

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摘要 目的:观察地佐辛抑制阑尾牵拉反射的效果。方法:选择行阑尾切除术的患者40例,ASAI~Ⅱ级,随机分为地佐辛组(A组)和芬太尼组(B组),各20例,于切皮前5min各静脉注射地佐辛5mg和芬太尼0.05mg,观察两组患者手术前、给药后5min、牵拉阑尾时的HR、MAP、R和Sp02,并观察恶心、呕吐、呼吸抑制、心率减慢等不良反应的发生情况。结果:A组比B组能更好地维持生命体征的平稳(P<0.05),两组都能有效地抑制阑尾牵拉反射(P>0.05),恶心、呕吐发生率无明显差异(P>0.05),呼吸抑制和心动过缓A组各1例,B组分别为6例和7例(P<0.05)。结论:地佐辛抑制阑尾牵拉反射的效果确切,呼吸、循环维持稳定,安全可靠。
作者 刘国艳
出处 《中国中西医结合外科杂志》 CAS 2011年第4期416-417,共2页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
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