辽宁绒山羊皮肤毛囊细胞凋亡特点的研究

Study on Hair Follicle Apoptosis of Liaoning Cashmere Goats

采用TUNEL法在一个生物年的周期内每隔两月对绒山羊体侧部的皮肤毛囊进行检测,观察毛囊细胞凋亡的周期性变化特点。结果表明,控制毛囊生长变化的凋亡细胞是成簇分布的,毛乳头的成纤维细胞很少有凋亡现象,细胞凋亡与毛囊周期性生长具有相关性,兴盛期毛囊凋亡细胞减少,退行期凋亡细胞显著增多。常年长绒型与季节长绒型品系在一年内的凋亡细胞变化情况基本一致,只是常年长绒型品系在兴盛前期的细胞凋亡明显低于季节长绒型品系。

TUNEL method was adopted for vertical and longitudinal slip section of hair follicles,which were from lateral part of Liaoning Cashmere goats during a year in different months,two months as an internal.The results indicated that the dead cells which controlling growth of hair follicle were clustering disposed,the phenomenon of apoptosis on mechanocyte of hair papilla was hardly found.The correlation between cycling of growth and apoptosis of hair follicle was found.The cells of apoptosis decreased during anagen,the cells of apoptosis increased prominently.The trend of changing on apoptosis of hair follicle,from the two types of Liaoning Cashemere goats,was coincidence fundamentally,compared with seasonal type,only the quantity of apoptosis cells were fewer before anagen.