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胰岛素样生长因子与胃肠道间质瘤

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摘要 胃肠道间质瘤(GIST)是一种消化道间叶源性肿瘤,发病机制不明,临床表现缺乏特异性,术前诊断存在较大困难。胰岛素生长因子是调节细胞增殖、分化和转化的关键因素,在肿瘤中,尤其是乳腺癌、前列腺癌和结肠癌的发生中起着重要作用。对胰岛素样生长因子的表达与GIST发病机制的相关性做一综述。
作者 蒋健 陈平
出处 《中国现代普通外科进展》 CAS 2011年第7期535-538,共4页 Chinese Journal of Current Advances in General Surgery
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