1,2,3-三取代贫电子环丙烷衍生物与苯硫酚反应的研究

Study on the Reaction of 1,2,3-Trisubstituted Electron Deficient Cyclopropane Derivatives with Thiophenol

报导1,2,3-三取代贫电子环丙烷衍生物顺-1-甲氧羰基-2-对位取代苯基-6,6-二甲基-5,7-二氧-螺-[2,5]-4,8-辛二酮与苯硫酚的反应.生成产物4 和5,产物4 经IR、MS、元素分析及1H、13 CNMR等确定其结构为β-甲氧羰基-γ-苯硫基-γ-对位取代苯基丁酸苯硫酯;产物5a经IR、MS、元素分析、1 HNMR等确定其结构为α-苯硫羰基-β-甲氧羰基-γ-对甲苯基-γ-丁酸内酯.

This paper deals with the reaction of 1,2,3 trisubstituted electron deficient cyclopropane derivatives cis 1 carbomethoxy 2 p substitutedphenyl 6,6 dimethyl 5,7 dioxo spiro [2,5] 4,8 octadiones with thiophenol to give the products 4 and 5a. The structures of reaction pro ducts 4 are founded to be S phenyl β carbomethoxy γ phenylthio γ p substitutedphenyl butyro thioates by IR, MS, microanalysis, 1H, 13 C NMR spectroscopies. The structure of reaction product 5a are found to be α carbophenylthio β carbomethoxy γ p methylphenylbutyro γ lactone by IR, MS, microanalysis, 1H, 13 C NMR spectroscopies. The reaction mechanisms for the formation of the products are proposed.