结构仿生羟基磷灰石多孔陶瓷的制备及其性能研究

Fabrication and Properties of Porous HA Ceramics with Bionic Structure

目的结合浸渍法和注浆成型工艺制备具有内疏外密天然骨结构仿生羟基磷灰石（hydroxyapatite,HA）多孔陶瓷。方法观察多孔陶瓷的截面形貌,表征其相组成,并测试多孔陶瓷的孔隙率和压缩强度。结果结构仿生HA多孔陶瓷的外层是孔隙率为17%的陶瓷块体,芯部为孔隙率在44－92%的三维连通多孔陶瓷,内外两部分的结合良好。结论通过浸渍次数可以控制芯部的孔隙率,其压缩强度主要依赖于外层的厚度,当外层厚度为4mm,芯部孔隙率为44%时,压缩强度可达40.3MPa;其生物降解性适中,14天时Ca2＋的溶出速率开始减缓。

Objective The porous hydroxyapatite ceramics with bionic structure were fabricated by the impregnation and slip casting.Method The phase,cross-section morphology,porosity,compression properties and biological degradability of the fabricated HA porous ceramics were characterized.Result The outside is the ceramic block with porosity of 17%,and the inside is 3-D interconnected porous ceramics with porosity range from 44% to 92%.No delamination found in the interface of the two parts of the HA porous ceramics.Conclusion Porosity of the inside was controlled by adjusting the impregnation times.The compressive strength of the HA porous ceramics with bionic structure depend on the thickness of the outside and can reach 40.3 MPa at porosity of 44% in the inside and thickness of 4 mm in the outside.The biological degradability is moderation,and the dissolution rate began slow after 14 days immersing in SBF.