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幽门螺杆菌感染与IL-8表达的关系 被引量:8

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摘要 幽门螺杆菌 (Hp)作为胃炎、胃十二指肠溃疡、胃癌、胃淋巴瘤等胃十二指肠疾病的重要致病因素已被广泛确认 ,作为非侵入性细菌 ,Hp诱导产生的IL 8作为第二信使招致粒细胞在局部聚集 ,是其引起炎症反应以及进一步病理损害的重要途径 ,本文就Hp及Hp的相关因素与IL 8产生的关系等问题作一综述 ,拟为进一步阐明Hp致病机制的研究提供理论基础。
作者 刘炯 许国铭
出处 《国外医学(内科学分册)》 1999年第12期527-529,542,共4页 Foreign Medical Sciences(Section of Internal Medicine)
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同被引文献27

  • 1王斌,徐少勇,卢光新,杜勇.cagA阳性幽门螺杆菌感染与老年胃十二指肠病的相关性[J].临床内科杂志,2004,21(11):749-750. 被引量:3
  • 2Wataru Shibata,Yoshihiro Hirata,Haruhiko Yoshida,Motoyuki Otsuka,Yujin Hoshida,Keiji Ogura,Shin Maeda,Tomoya Ohmae,Ayako Yanai,Yuzo Mitsuno,Naohiko Seki,Takao Kawabe,Masao Omata.NF-κB and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection[J].World Journal of Gastroenterology,2005,11(39):6134-6143. 被引量:13
  • 3马利川.残胃癌的研究[J].新消化病学杂志,1997,5(5):333-333. 被引量:5
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  • 6Crabtree JE, Peichl P, Wyatt JI, et al. Gastric interluekin-8 and IgA IL-8 autoantibodies in helicobacer pylori infection[J]. Scand J Immunol, 1993,37:65.
  • 7Loffeld RJLF,Loffeld BCAJ,Arends JW,et al. Retrospective study of eampyloba cter-likeorganisms in patients undergoing partial gastrectomy. J Clin Pathol 1988; 41: 1313
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  • 9Fujiwara K,Arakawa T,Fukuda T.Interlenkin-8 stimulates leukocyte migration across a monolayer of cultured rabbit gastric epithelial cells.Effect associated with the impairment of gastric epithelial barrier function [J].Dig Dis Sci,1997,42(6):1210-1215.
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