摘要
采用体外细胞培养方法，研究共轭亚油酸（ＣＬＡ）对人胃腺癌细胞（ＳＧＣ－７９０１）生长的影响。ＣＬＡ的剂量分别为２５、５０、１００和２００μｍ ｏｌ／Ｌ，以乙醇为溶剂对照。结果表明：ＣＬＡ 能抑制ＳＧＣ－７９０１细胞的增殖、细胞核分裂、集落形成和细胞ＤＮＡ的合成。
The effects of conjugated linoleic acid(CLA) on human gastric carcinoma cell line(SGC 7901) were studied in cell culture. The four levels of CLA in medium were designed as 25,50,100 and 200μmol/L, and the dissolvent control being ethane. The result displayed that CLA could inhibit the cell proliferation, cellular mitosis, cell clone formation and DNA synthesis and induce cellular differentiation of SGC 7901 cells.
出处
《卫生研究》
CAS
CSCD
北大核心
1999年第6期353-355,共3页
Journal of Hygiene Research
基金
国家自然科学基金
关键词
共轭亚油酸
人胃腺癌细胞
抑制
胃癌
conjugated linoleic acid (CLA),human gastric carcinoma cell line (SGC 7901)
