早期缺血性进展性脑卒中患者血清同型半胱氨酸和hs-CRP的相关研究

The Research of Homocysteine and High Sensitivity C-reactive Protein in Early Ischemic Progress Stroke Patients

目的研究早期缺血性进展性脑卒中患者血清同型半胱氨酸与超敏C反应蛋白的变化。方法回顾分析我院226例缺血性进展性脑卒中患者和197例完全性脑卒中患者早期的同型半胱氨酸和超敏C反应蛋白资料。并比较不同大小梗死灶组的血清同型半胱氨酸与超敏C反应蛋白差异。结果缺血性进展性脑卒中组的同型半胱氨酸(17.89±2.98,20.39±3.34,23.12±4.76,25.44±3.89,24.39±3.69,22.76±4.09,21.99±5.93)高于完全性脑卒中组。而缺血性进展性脑卒中组的超敏C反应蛋白含量在各个测量时间也高于完全性脑卒中组(P<0.05)。且梗死灶越大,同型半胱氨酸及超敏C反应蛋白水平越高。结论血清同型半胱氨酸和超敏C反应蛋白可作缺血性进展性脑卒中的重要早期诊断指标之一。

Objective To discuss the homocysteine and high sensitivity C-reactive protein in early Ischemic progress stroke patients. Methods The data of homocysteine and high sensitivity C-reactive protein in 226 early Ischemic progress stroke patients and 197 completeness stroke was Reviewed. And comparing different size infarcts group of serum homocysteine and allergic c-reactive protein differences. Results The group of homocysteine in Ischemic progress stroke patients （ 17.89 ± 2.98,20.39 ± 3.34,23.12 ± 4.76, 25.44± 3.89,24.39 ± 3.69,22.76 ± 4.09,21.99 ± 5.93 ） was higher than the group of completeness stroke, and the also the same solution in high sensitivity C-reactive protein. Conclusion The homocysteine and high sensitivity C-reactive protein may act as one of the Important early diagnosis indexes in Ischemic progress stroke patients.