银花合剂雾化吸入治疗婴幼儿病毒性肺炎的临床与实验研究

Clinical and Experimental Study on Yinhua Mixture Aerosol in Treating Infantile Viral Pneumonia

目的:探讨银花合剂对病毒性肺炎的治疗作用及机理研究。方法:用银花合剂雾化吸入治疗婴幼儿病毒性肺炎69例,并与用庆大霉素雾化吸入治疗的33例作对照,并进行了动物镇咳、平喘等药效学实验。结果:治疗组和对照组显效率分别为580%、273%,总有效率分别为957%和697%,治疗组疗效优于对照组(P<005)。药效学实验证实银花合剂有退热、平喘和祛痰作用。结论:银花合剂具有退热、镇咳、平喘、祛痰作用。

Objective: To explore the therapeutic effect of using Yinhua mixture aerosol in treating infantile viral pneumonia and its mechanism. Methods: Comparing sixty nine infantile viral pneumonia patients using Yinhua mixture aerosol with 33 infantile viral pneumonia patients using gentamycin, pharmacodynamical animal experiments of anti tussis and anti asthma were also observed. Results: The markedly effective rate of Yinhua mixture aerosol and gentamycin aerosol were 58.0% and 27.3% respectively, while the total effective rate of these two drugs was 95.7% and 69.7% respectively. Experimental study revealed that Yinhua mixture was effective in antifebrile, anti asthma and expectorative effect, which was better than that of gentamycin (P<0 05). Conclusion: Yinhua mixture areosol is effective in antifebrile, anti asthma, and expectorative effect.