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阿托伐他汀对扩张型心肌病心力衰竭的影响研究 被引量:1

Effect of atorvastatin on patients with dilated cardiomyopathy heart failure
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摘要 目的:探讨阿托伐他汀对扩张型心肌病(DCM)心力衰竭的治疗作用。方法:46例DCM心衰住院患者,随机分为对照组和试验组,每组23例。两组患者均心衰常规治疗,试验组加用阿托伐他汀20mg/天,共1年。测定治疗后两组患者心功能指标。结果:治疗后,试验组患者六分钟步行距离明显延长,LVEF明显提高,BNP及CRP均显著下降。结论:托伐他汀可进一步改善DCM心力衰竭患者的心功能。 Objective:To study the Effect of atorvastatin on patients with dilated cardiomyopathy(DCM) heart failure.Methods:46 hospital patients with DCM heart failure were randomly divided into control group and experiment group,23 cases per group.All patients treated with conventional anti-heart failure,the patients of experiment group took the added atorvastatin,20mg per day,for 1 year.Heart function of every patient were tested before and after therapy.Results:In experiment group,the six minutes walk distance was obviously longer,LVEF was notably increased,BNP and CRP were significantly lower.Conclusions:Atorvastatin may improve heart function of patients with DCM heart failure.
出处 《医学信息(中旬刊)》 2011年第8期3905-3906,共2页 Medical Information Operations Sciences Fascicule
关键词 阿托伐他汀 扩张型心肌病 心力衰竭 Atorvastatin Dilated cardiomyopathy Heart failure
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  • 1Richardson P,McKenna W,Bristow W,et al.Report of the 1995 World Organization/Intemational Society and Federation of CardiologyTask Force on the definition and classification of cardiomyopathies.Circulation,1996,93841-842.
  • 2扩张型心肌病.见:马文珠,张寄南,主编.心肌疾病.南京:江苏科学技术出版社,2000:64-69.
  • 3Kaneko K,Kanda T,Yamauchi Y,et al.C-reactive protein in dilated cardiomyopathy.Cardiology,1999,91:215-219.

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