脑利钠肽治疗慢性心力衰竭临床分析

Clinical analysis on brain natriuretic peptide treatment of chronic heart failure

目的:观察重组人脑利钠肽治疗慢性心衰急性临床疗效,提高慢性心力衰竭的临床治疗效率,改善患者生活质量。方法:回顾性分析2009年3月～2011年3月我院采用重组人脑利钠肽治疗的46例慢性心力衰竭患者的临床资料,并以同期采用硝普钠治疗的46例患者,为对照组,比较两组患者治疗效果。结果:观察组治疗有效率明显高于对照组,组间比较差异具有统计学意义(P<0.05)。经过治疗,观察组患者左心射血分数明显提高,改善效果优于对照组,组间比较差异具有统计学意义(P<0.05)。结论:重组人脑利钠肽治疗慢性心力衰竭安全有效,值得临床推广。

Objective：Observe restructuring the brain natriuretic peptide therapy for chronic heart failure acute clinical curative effect,improve the clinical treatment of chronic hf efficiency,improve the quality of life of the patients.Methods：Retrospective analysis March 2009 to March 2011 by group of our human brain natriuretic peptide treatment of 46 cases of chronic heart failure patients with clinical information,and using the same （sodium treatment at 46 patients,as control group,compared with two groups of patients therapeutic effect.Results：The observation group therapy significantly higher than control group,and group efficiency between comparative differences are statistically significant （P0.05）.After treatment,patients with the observation group left heart ejection fraction was improved obviously,improve effect between groups than control group,a statistically significant comparative differences （P0.05）.Conclusion：Recombinant human brain natriuretic peptide safe and effective treatment of chronic heart failure,worth clinical promotion.